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Mass Spectrometry for Microbial Proteomics

Editat de Haroun N Shah, Saheer E Gharbia
en Limba Engleză Hardback – 23 aug 2010
Die neuesten Fortschritte in der Proteomik, die zum großen Teil durch die Entwicklungen in der Massenspektronomie vorangetrieben werden, zeigen immer wieder die Komplexität und Vielfalt pathogener Mechanismen in Mikroben als Verursacher und Verstärker infektiöser Erkrankungen. Eine neue Ära in der medizinischen Mikrobiologie erfordert daher einen schnellen Wechsel der heutigen Verfahren hin zu hoch leistungsfähigen Analysesystemen für die Diagnose mikrobieller Pathogene. Dieses Buch deckt die ganze Bandbreite mikrobiologischer Anwendungen der Proteomik und Massenspektronomie ab. In sechs Kapiteln werden die Abläufe dargestellt, mit denen die meisten mikrobiologischen Labors das Thema angehen: Übergang, Werkzeuge, Vorbereitung, Profiling-by-Pattern, Zielproteine und Datenanalyse.
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Specificații

ISBN-13: 9780470681992
ISBN-10: 0470681993
Pagini: 534
Dimensiuni: 176 x 251 x 30 mm
Greutate: 1.17 kg
Editura: Wiley
Locul publicării:Chichester, United Kingdom

Public țintă

Microbiologists and technicians in microbiology laboratories, h ealth professionals, a nalytical chemists involved in applying mass spectrometry technologies to microbiological research. Also, i nstitutions dealing with emerging infections or bioterrorism.

Notă biografică

Professor Haroun N. Shah is Head of Molecular Identification Services Unit at the Centre for Infections, Health Protection Agency, London. The Centre for Infections provides infectious disease surveillance and microbial identification services, co-ordinating the investigation and cause of national and uncommon outbreaks of diseases. Haroun holds several chairs at various universities and spent 25 years in academic life at the University of London.
Professor Saheer E. Gharbia is Head of the Applied and Functional Genomics Unit at the HPA Centre for Infections. She has a PhD in molecular Genetics and Biochemistry, and has held various academic positions at the University of London and McGill University, Canada.

Descriere

New advances in proteomics, driven largely by developments in massspectrometry, continue to reveal the complexity and diversity ofpathogenic mechanisms among microbes that underpin infectiousdiseases.