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Lysosomes

Editat de Frederick R Maxfield, James M Willard, Shuyan Lu
en Limba Engleză Hardback – 24 iun 2016
Discussing recent findings, up-to-date research, and novel strategies, the book integrates perspectives from pharmacology, toxicology, and biochemistry to illustrate the potential of lysosomes in drug discovery and development. * Explores basic principles and properties of lysosomes that allow them to act as regulators of cell metabolism, therapeutic targets, and sites for activation of drug conjugates * Discusses the role of lysosomes in metabolism, drug targeting, apoptosis, cancer, aging, inflammation, autophagy, metabolism, toxicity, and membrane repair * Introduces new pathways in therapeutic development and new mechanisms in drug development
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Specificații

ISBN-13: 9781118645154
ISBN-10: 1118645154
Pagini: 544
Dimensiuni: 157 x 236 x 36 mm
Greutate: 0.93 kg
Editura: Wiley
Locul publicării:Hoboken, United States

Public țintă

Cell biologists and biochemists interested in the properties and functions of lysosomes

Scientists and researchers in biotech and pharmaceutical industries

Medicinal chemists, pharmacologists, toxicologists, biochemists, cell and molecular biologists, clinicians, immunologists, oncologists

Regulatory affairs, regulatory science, and government professionals in toxicology and drug development

Descriere

This book comprehensively reviews lysosomes principles, properties, and role in disease and therapeutics and features perspectives from cell biology, pharmacology, toxicology, and biochemistry to illustrate their drug discovery and development potential.