Joan is a thirtysomething ICU doctor at a busy New York City hospital. The daughter of Chinese parents who came to the United States to secure the American dream for their children, Joan is intensely devoted to her work. When Joan's father suddenly dies and her mother returns to America to reconnect with her children, a series of events sends Joan spiralling out of her comfort zone just as her hospital, her city, and the world are forced to reckon with a health crisis more devastating than anyone could have imagined.