Introduction to Systems Biology
Editat de Sangdun Choien Limba Engleză Hardback – 16 iul 2007
Informative and cutting-edge, this volume presents a clear and intuitive illustration of the biological systemic approaches and introduces ideal computational methods for research. Introduction to Systems Biology is an indispensable resource, providing a first glimpse into the state-of-the-art in systems biology.
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Specificații
ISBN-13: 9781588297068
ISBN-10: 1588297063
Pagini: 560
Ilustrații: XVI, 542 p. 163 illus., 2 illus. in color.
Dimensiuni: 183 x 260 x 35 mm
Greutate: 1.24 kg
Ediția:2007
Editura: Humana
Locul publicării:Totowa, NJ, United States
ISBN-10: 1588297063
Pagini: 560
Ilustrații: XVI, 542 p. 163 illus., 2 illus. in color.
Dimensiuni: 183 x 260 x 35 mm
Greutate: 1.24 kg
Ediția:2007
Editura: Humana
Locul publicării:Totowa, NJ, United States
Public țintă
ResearchCuprins
Scientific Challenges in Systems Biology.- Bringing Genomes to Life: The Use of Genome-Scale In Silico Models.- From Gene Expression to Metabolic Fluxes.- Experimental Techniques for Systems Biology.- Handling and Interpreting Gene Groups.- The Dynamic Transcriptome of Mice.- Dissecting Transcriptional Control Networks.- Reconstruction and Structural Analysis of Metabolic and Regulatory Networks.- Cross-Species Comparison Using Expression Data.- Methods for Protein-Protein Interaction Analysis.- Genome-Scale Assessment of Phenotypic Changes During Adaptive Evolution.- Location Proteomics.- Theoretical and Modeling Techniques.- Reconstructing Transcriptional Networks Using Gene Expression Profiling and Bayesian State-Space Models.- Modeling Spatiotemporal Dynamics of Multicellular Signaling.- Kinetics of Dimension-Restricted Conditions.- Mechanisms Generating Ultrasensitivity, Bistability, and Oscillations in Signal Transduction.- Employing Systems Biology to Quantify Receptor Tyrosine Kinase Signaling in Time and Space.- Dynamic Instabilities Within Living Neutrophils.- Efficiency, Robustness, and Stochasticity of Gene Regulatory Networks in Systems Biology: ? Switch as a Working Example.- Applications, Representation, and Management of Signaling Pathway Information: Introduction to the SigPath Project.- Methods and Software Platforms for Systems Biology.- SBML Models and MathSBML.- CellDesigner: A Graphical Biological Network Editor and Workbench Interfacing Simulator.- DBRF-MEGN Method: An Algorithm for Inferring Gene Regulatory Networks from Large-Scale Gene Expression Profiles.- Systematic Determination of Biological Network Topology: Nonintegral Connectivity Method (NICM).- Storing, Searching, and Disseminating Experimental Proteomics Data.- Representing andAnalyzing Biochemical Networks Using BioMaze.
Caracteristici
Basic explanation of how to use computational methods to explain underlying biological meanings Introduction into state-of-the-art systems biology Contains typical approaches to experimental design, both wet-lab and computational Includes supplementary material: sn.pub/extras