As men fall to the mist, the age of womankind begins to rise. The world as we know it ends when an attack on the U.S. unleashes bombs that deliver fire and biological destruction. The bombs have also brought the green mist. If breathed in, it is deadly to all men - but alters the body chemistry of many women, imbuing them with superhuman abilities. As a group of women cross the Pacific Northwest, trying to find a safe place to ride out the apocalypse, the women soon learn they can't trust anyone, and with fresh danger around every corner, it will take all their powers to save themselves.