Where does my body begin? Where does it end? What is inside my body? What is outside? What is primary? What is secondary? What is natural? What isartificial? Science fiction has long imagined a future fusion of humanity with technology. Today, many of us--especially people with health issues such as autoimmune diseases--have functionally become hybrids connected to other machines and to other bodies. The combination of artificial intelligence with implants, transplants, prostheses, and genetic reprogramming is transforming medical research and treatment, and it is now also transforming what we thought was human nature.