This handbook provides information for trajectory designers and mission planners to determine Earth-Mars and Mars-Earth mission opportunities for the years 2009-2024. These studies were performed in support of a human Mars mission scenario that will consist of two cargo launches followed by a piloted mission during the next opportunity approximately 2 years later. "Porkchop" plots defining all of these mission opportunities are provided which include departure energy, departure excess speed, departure declination arrival excess speed, and arrival declinations for the mission space surrounding each opportunity. These plots are intended to be directly applicable for the human Mars mission scenario described briefly herein. In addition, specific trajectories and several alternate trajectories are recommended for each cargo and piloted opportunity. Finally, additional studies were performed to evaluate the effect of various thrust-to-weight ratios on gravity losses and total time-of-flight tradeoff, and the resultant propellant savings and are briefly summarized.