Comic's most crazed champion is back! Trapped in a "Hospital for the Mentally Unhinged," our loony lion-heart must fight for her freedom and survival. With the help of her trusty new side-kick, the forces of evil are on the run. Or, maybe she's just imagining this. Either way, Jane's back and she's crazier than ever! Soon be a television show! Take youthful energy. Add in some over-active imagination. Mix in some powdered donuts. Sprinkle it with delusional disorder and you get ... Insane Jane! Will Jane save the day? Will Jane destroy the world? Will she remember to take her medication?