This volume presents peer-reviewed papers accepted for presentation at the 2026 International Conference on Information Technology & Systems (ICITS’26), held at the Universidad Tecnológica de Honduras (UTH), Roatán Island, Honduras, from February 16 to 18, 2026. ICITS’26 provides an international platform for researchers and practitioners to share cutting-edge research, innovative solutions, and practical experiences in the rapidly evolving field of Information Technology & Systems. The conference promotes interdisciplinary dialogue and fosters collaboration across academia, industry, and public institutions worldwide. The book covers a broad range of contemporary topics, including Information and Knowledge Management; Organizational Models and Information Systems; Software and Systems Modeling; Software Systems, Architectures, Applications, and Tools; Multimedia Systems and Applications; Computer Networks, Mobility, and Pervasive Systems; Intelligent and Decision Support Systems; Big Data Analytics and Applications; Human–Computer Interaction; Ethics, Computers, and Security; Health Informatics; Information Technologies in Education; and Media, Applied Technology, and Communication. Bringing together contributions from an international community of scholars, this volume offers valuable insights into emerging technologies, theoretical advances, and real-world applications. The primary audience includes postgraduate students, researchers, and academics in Information Systems and Technologies. It will also be of interest to advanced undergraduate students and professionals working in related technological and interdisciplinary domains.