In the foggy streets of Victorian London, Dr Ezra Forge has created a formula that will eradicate mankind's weakness to disease. He knows it will change the face of medical history by putting a stop to infection and fatal illnesses. But the formula has a dark secret, and it is only when the doctor's wife falls critically ill that the secret is revealed, one which either transforms the mild mannered doctor into a vicious monster, or simply awakens one within him.