This book provides a detailed survey of the more powerful and less conventional HPLC detection methods available today. Addressing both theory and application, experts give their assessment of some of the most promising detection methods being developed. Long lived luminescence, near-infrared semiconductor laser fluorescence, and HPLC-mass spectrometry are among the methods discussed. In addition, an entire chapter is devoted to showing how the ultimate power of NMR may be combined with HPLC. This book serves the needs of chromatographers who find their work restricted by the limits of conventional HPLC detection methods, and whose practical needs dictate the use of newer, more powerful methods.