This Handbook represents an innovative response to the trend toward increased medical complexity in nursing home patients, and to the demand for greater behavioral health collaboration in their treatment plans. It is a portable reference guide for health care professionals who want to understand the recommended cognitive-behavioral approaches for the co-morbid psychological issues impacting medical conditions in nursing facilities, including diabetes, respiratory disease, obesity and chronic pain, and diagnoses requiring rehabilitation, such as stroke and fractures. An array of assessment measures are discussed, and cognitive-behavioral treatment protocols are reviewed for twelve acute and chronic medical conditions. This Handbook will serve as an indispensable tool to help patients mentally manage their disabling medical conditions.