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Gynecologic Radiation Therapy de Akila N. Viswanathan

Gynecologic Radiation Therapy

Editat de Akila N. Viswanathan, Christian Kirisits, Beth E. Erickson, Richard Pötter
en Limba Engleză Hardback – 29 oct 2010

Provocarea majoră în oncologia ginecologică modernă rezidă în precizia livrării dozei, minimizând în același timp toxicitatea asupra organelor adiacente. Gynecologic Radiation Therapy abordează direct această necesitate, marcând sfârșitul unei ere de peste șase decenii în care planificarea tratamentului pentru cancerul de col uterin a rămas statică. Remarcăm modul în care lucrarea documentează schimbarea de paradigmă de la tehnicile convenționale bidimensionale către protocoalele riguroase bazate pe imagistică secvențială. Structura volumului este una progresivă, pornind de la fundamentele radiologice ale malignităților ginecologice și avansând spre utilitatea clinică a radioterapiei cu fascicul extern (EBRT). Apreciem în mod deosebit secțiunile dedicate brahiterapiei ghidate imagistic, unde sunt detaliate aspectele medicale, biologice și fizice ale planificării 3D. Autorii nu se limitează la teorie, ci oferă abordări practice privind selecția aplicatoarelor și tehnicile de inserție, esențiale pentru obținerea unui control local optim. Suntem de părere că acest volum reprezintă o alternativă tehnică riguroasă la Radiation Therapy Techniques for Gynecological Cancers de Kevin Albuquerque. În timp ce titlul lui Albuquerque servește drept ghid practic pas-cu-pas pentru simulare și conturare, lucrarea editată de Akila N. Viswanathan și Richard Pötter pune un accent mai profund pe fundamentarea radiobiologică și pe consensul internațional privind noile tehnologii. De asemenea, față de Gynecologic Radiation Oncology: A Practical Guide de Patricia Eifel, care se concentrează pe experiența clinică vastă a unui singur centru (MD Anderson), acest manual oferă o perspectivă multi-instituțională asupra implementării IMRT și a brahiterapiei cu rată mare a dozei (HDR).

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Specificații

ISBN-13: 9783540689546
ISBN-10: 3540689540
Pagini: 320
Ilustrații: IX, 308 p.
Dimensiuni: 160 x 241 x 23 mm
Greutate: 0.65 kg
Ediția:2011
Editura: Springer
Locul publicării:Berlin, Heidelberg, Germany

Public țintă

Professional/practitioner

De ce să citești această carte

Recomandăm această lucrare medicilor radioterapeuți și fizicienilor medicali care doresc să implementeze protocoale de ultimă oră în tratamentul cancerelor de col uterin și endometru. Cititorul câștigă o înțelegere profundă a conturării adaptive și a planificării 3D, elemente critice pentru îmbunătățirea rezultatelor clinice și reducerea efectelor secundare pe termen lung în oncologia ginecologică.

Despre autor

Echipa editorială este formată din lideri mondiali în domeniul radioterapiei oncologice. Akila N. Viswanathan este recunoscută pentru contribuțiile sale în standardizarea brahiterapiei ginecologice, în timp ce Richard Pötter a jucat un rol esențial în dezvoltarea ghidurilor GEC-ESTRO, care au revoluționat tratamentul cancerului de col uterin prin utilizarea RMN-ului în planificarea brahiterapiei. Expertiza lor combinată asigură o abordare echilibrată între rigoarea fizicii medicale și necesitățile clinice ale pacientelor, transformând acest manual într-o referință de bază pentru practica oncologică contemporană.

Descriere scurtă

Recent advances in the treatment of gynecologic malignancies led to a new worldwide consensus to introduce image guidance to gynecologic radiation therapy, particularly to brachytherapy. The book summarizes the changed practice of management: treatment planning for cervical cancer, not modified for over 60 years, has been shifted to an image-based approach, endometrial cancer management with an increase in the use of chemotherapy and vaginal brachytherapy, and vaginal cancer therapy including image guidance and high-dose delivery with IMRT.

Cuprins

Section 1:Radiologic Imaging of Gynecologic MalignanciesGeneral Considerations.-Section 2: Clinical Utility of Imaging for EBRTIssues with Imaging in the Use of Radiation for Locally Advanced Cervical Cancer.-The Use of Image Guidance in External Beam Planning.-The Use of Imaging for 3D Conformal and for IMRT in Vaginal/Vulvar cancer.-Section 3: Image Guided Brachytherapy, Medical and Biological Treatment Planning Adaptive Contouring of GTV, CTV and Organs and Ris.-Medical Aspects of Treatment Planning.-Radiobiologic Aspects of Brachytherapy in the Era of 3D Imaging.-Section 4: Image Guided Brachytherapy: Physics Treatment Planning3D Image Guided Treatment Planning.-Section 5: Practical ApproachesApplicator Selection, Insertion adn Imaging of 3D Image-Based Intracavitary Brachytherapy.-Post-operative Vaginal Cylinder Brachytherapy.- Template-Guided Interstittial BrachytherapySection 6: Outcomes.-Clinical Outcomes of 3D External Beam and Brachytherapy.

Notă biografică

Akila Viswanathan, M.D., M.P.H. has served as the Chief of Gynecologic Radiation Oncology and Director of the 3D Image-Guided Gynecologic Brachytherapy Program at the Dana-Farber/Brigham and Women’s Cancer Center, Harvard Medical School, since 2002. Dr. Viswanathan completed her undergraduate studies at Harvard University in Cambridge, Massachusetts, and received her medical degree from the University of Pittsburgh School of Medicine. She completed her residency at the Harvard Joint Center for Radiation Therapy and earned both Master’s in Public Health and Master’s of Science in Epidemiology degrees at the Harvard School of Public Health. At the Dana-Farber/Brigham and Women’s, she led the development and growth of the gynecology practice and designed clinical trials of real-time MRI-based image-guided brachytherapy and CT-based imaging for gynecologic cancer patients. She implemented the first use of IMRT techniques at the Dana-Farber/Brigham and Women’s for selected gynecologic cancer patients. In addition to clinical outcomes, Dr. Viswanathan’s research focuses on risk factors and prevention of endometrial cancer, using the Nurses’ Health Study. In 2005 she was awarded a National Institutes of Health K-award to further these research pursuits. She is actively involved in protocol development, serving as principal investigator for an accruing trial, and works with the Radiation Therapy Oncology Group Gynecology Steering Committee to study novel therapeutics in gynecologic cancers. Dr. Viswanathan has lectured widely on gynecologic malignancies and their treatment. Her lectures have brought image-guided brachytherapy and its status in the U.S. to the forefront at local, regional, national and international conferences. She has also led panels, courses and schools for the American Brachytherapy Society and the American Society for Therapeutic Radiology and Oncology, and has served on the board of directors of the American BrachytherapySociety for 3 years. She serves on national and international committees including the Gynecologic Cancer Intergroup and the Gynecologic Cancer Task Force for the National Cancer Institute. Dr. Christian Kirisits studied technical physics at the Vienna University of Technology and graduated 2001 as a Doctor of Technical Science (Dr. techn.). In the same year he got a staff position as medical physicist at the Department of Radiotherapy, Medical University of Vienna after working there as a research fellow before. The main field of research was experimental and Monte Carlo dosimetry for endovascular brachytherapy. After an additional thesis (Habilitation) in Medical Physics he became Associate Professor at the Medical University of Vienna. During the last years he focussed on all aspects of modern brachytherapy, especially image guided approaches for gynaecological radiotherapy. He is a member of the GEC ESTRO committee and working groups of GEC ESTRO (BRAPHYQS -Brachytherapy physics, GYN group). Beside teaching activities at the Medical University he was involved as teacher and organizer at various postgraduate courses including the Endovascular, the GYN, and the Image Guided Radiotherapy teaching course of ESTRO. His most recent appointments include the position as one of the coordinators for the revision of ICRU 38 and the EMBRACE trial.Dr. Erickson is a Professor of Radiation Oncology at the Medical College of Wisconsin. She is a Trustee of the American Board of Radiology and a past-president of the American Brachytherapy Society. She is a fellow of the American College of Radiology and serves as Vice-Chair for the ACR QRRO Cervix Committee, as well as on the ACR Standards and Accreditations Committee. She is a member of the RTOG Gynecologic Committee. Internationally, she has served on the GEC-ESTRO committee, participates in the EMBRACE Trial, and serves as co-chair of the Trans-Atlantic Image-based Brachytherapy Working Group.Richard Pötter MD hasbeen Professor and Head of the Department of Radiotherapy at the Medical University of Vienna/Vienna General Hospital since 1993. After graduation in medicine in Münster, Germany, he became diagnostic radiologist and radiation oncologist. He has been working continuously on imaging in radiotherapy since his “Habilitation” on this topic in 1989. His major clinical oncology areas have been paediatrics, prostate and gynaecology. He was president of the European Brachytherapy Group GEC ESTRO from 1999-2003. Since 2004 he has been coordinator of the European network for 3D image guided gynaecological brachytherapy (GynGECESTRO) where the international study EMBRACE was developed in which he is principal investigator since 2008. Richard Pötter is editor for brachytherapy in the “green” journal and also associate editor in the “blue journal”. He has been chairman of the ESTRO committee for Education since 2006 (ESTRO school). The major focus of his activities in Vienna and abroad during the last decade has been on the development of gynaecologic radiation therapy linking the progress in imaging to the potential of radiotherapy, mainly brachytherapy.

Caracteristici

Covers the most recent advances in gynecologic image-based radiation therapy Includes the changed practice of management of gynecologic brachytherapy Written by an international panel of experts Includes supplementary material: sn.pub/extras