Gallopamil: Pharmacological and Clinical Profile of a Calcium Antagonist

Gallopamil (D 600) — a Calcium Antagonist of High Potency and Specificity. Effects on the Myocardium and Pacemakers.- Blockade of the Ca2+-dependent Bioelectrical Automaticity and Electromechanical Coupling of Smooth Muscle Cells by Gallopamil (D 600).- Studies on the Mechanism of Action of D 600 on Isolated Myocytes.- Studies in Vitro and in Vivo on the Effect of Gallopamil on Coronary Vessels.- Electrophysiological Studies with Gallopamil on the Myocardium of the Human Ventricle.- Studies on the Cardiovascular Effects of Gallopamil.- Antihypoxic Effect of Gallopamil in the Brain.- Pharmacokinetics and Metabolism of Gallopamil.- The Effect of Gallopamil on the Haemodynamics of Patients with Coronary Heart Disease.- Pharmacodynamics and Electrophysiology of Gallopamil.- Anti-anginal Effect of the Calcium Antagonist Gallopamil.- Effect of Gallopamil on Coronary Arteries and Haemodynamics.- Effect of Gallopamil (D 600) on the ECG During Exercise, in Coronary Heart Disease.- Anti-anginal Effect of Gallopamil as Compared with Nifedipine.- Results of an Open Multicentre Study with 455 Patients with Coronary Heart Disease, Treated with Gallopamil for 1 Year.- Acute and Long-term Effects of Gallopamil in Patients with Stable Angina Pectoris.