Fundamentals of Brain Organoids for Neurological Diseases
Editat de Balachandar Vellingiri, Mahalaxmi Balachandaren Limba Engleză Paperback – 20 oct 2025
- Presents the steps involved in the generation of brain organoids from HiPSCs onwards
- Summarizes the importance of organoids in understanding various neurodevelopmental disorders
- Reviews the ongoing clinical trials using brain organoids
- Discusses ethical considerations when conducting organoid research
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Specificații
ISBN-13: 9780443298981
ISBN-10: 044329898X
Pagini: 360
Dimensiuni: 152 x 229 x 21 mm
Greutate: 0.67 kg
Editura: ELSEVIER SCIENCE
ISBN-10: 044329898X
Pagini: 360
Dimensiuni: 152 x 229 x 21 mm
Greutate: 0.67 kg
Editura: ELSEVIER SCIENCE
Cuprins
Section I An overview about Organoids
1. An overview on organoids - Past, present and future scenario of organoids
Section II Neurodevelopmental disorder
2. A brief introduction about neurodevelopmental disorders
3. Use of brain organoids for autism
4. Role of brain organoids in Rett Syndrome
5. Brain organoids in bipolar disorder: Unraveling mechanisms and therapeutic approaches
6. Ongoing clinical trials on use of brain organoids for neurodevelopmental disorders
Section III Neurodegenerative diseases
7. An overview of Neurodegenerative diseases
8. Use of brain organoids for Parkinson’s disease and Alzheimer’s disease
9. Application of brain organoids in Huntington’s disease
10. Ongoing clinical trials on use of brain organoids for neurodegenerative diseases (Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, etc.)
Section IV Methods involved in organoids development
11. How human-induced pluripotent stem cells are derived into organoids
12. Elements required and days involved in organoid generation
Section V – Application and advancement of Brain organoids
13. Brain organoids – Challenges while constructing organoids
14. Existing drug targeting and research using brain organoids
Section VI - Ethical consideration while conducting organoids research
15. Ethical consideration while conducting organoids research
Section VII - Future perspective and concluding remarks
16. Future directions and conclusion
1. An overview on organoids - Past, present and future scenario of organoids
Section II Neurodevelopmental disorder
2. A brief introduction about neurodevelopmental disorders
3. Use of brain organoids for autism
4. Role of brain organoids in Rett Syndrome
5. Brain organoids in bipolar disorder: Unraveling mechanisms and therapeutic approaches
6. Ongoing clinical trials on use of brain organoids for neurodevelopmental disorders
Section III Neurodegenerative diseases
7. An overview of Neurodegenerative diseases
8. Use of brain organoids for Parkinson’s disease and Alzheimer’s disease
9. Application of brain organoids in Huntington’s disease
10. Ongoing clinical trials on use of brain organoids for neurodegenerative diseases (Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, etc.)
Section IV Methods involved in organoids development
11. How human-induced pluripotent stem cells are derived into organoids
12. Elements required and days involved in organoid generation
Section V – Application and advancement of Brain organoids
13. Brain organoids – Challenges while constructing organoids
14. Existing drug targeting and research using brain organoids
Section VI - Ethical consideration while conducting organoids research
15. Ethical consideration while conducting organoids research
Section VII - Future perspective and concluding remarks
16. Future directions and conclusion