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Fas Signaling

Editat de Harald Wajant
en Limba Engleză Hardback – 12 apr 2006
Fas Signaling is focused on the signaling mechanisms and biology of the prototypic death receptor Fas, also called CD95 or APO-1. The chapters of this book cover, besides the well recognized apoptosis-related functions of Fas, its emerging role as a proinflammatory cytokine and as an inducer of alternative forms of cell death. Fas Signaling aims to provide the reader with an up-to-date survey of the various aspects of Fas biology and the open questions of the field are addressed. This title is intended for Ph.D and post-doctoral students starting to work in the field, but is also useful for everyone with an interest in the biology of this exciting molecule.
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Specificații

ISBN-13: 9780387321721
ISBN-10: 0387321721
Pagini: 172
Ilustrații: VIII, 160 p. 32 illus., 4 illus. in color.
Dimensiuni: 160 x 241 x 16 mm
Greutate: 0.46 kg
Ediția:2006
Editura: Springer
Locul publicării:New York, NY, United States

Public țintă

Research

Cuprins

FasL and Fas.- FasL-Independent Activation of Fas.- Role of Ceramide in CD95 Signaling.- Regulation of Fas Signaling by FLIP Proteins.- Fas-Induced Necrosis.- Fas—More Than an Apoptosis Inducer.- Retrograde Fas Ligand Signaling.- FasL and Fas in Liver Homeostasis and Hepatic Injuries.- Fas-Activation, Development and Homeostasis of T Cells.- The FasL-Fas System in Disease and Therapy.- Tools for Activation and Neutralization of Fas Signaling.

Caracteristici

Written by experts in the field and cover not only the well established apoptosis-related aspects of Fas biology, but also take up new developments in the field recognizing Fas as a proinflammatory cytokine and as an inducer of alternative forms of cell death Includes supplementary material: sn.pub/extras