The production and the properties of nuclei in extreme conditions, such as high isospin, temperature, angular momenta, large deformations etc., have become the subject of detailed investigations in all scientific centers. The main topics discussed at the Symposium were: Synthesis and Properties of Exotic Nuclei; Superheavy Elements; Rare Processes and Decays; Physics with Radioactive Ion Beams; Experimental Facilities; and Future Projects.This book provides a comprehensive overview of the newest results of the investigations in the main scientific centers such as GSI, GANIL, RIKEN, MSU, and JINR.