This book constitutes the refereed proceedings of the International Conference on Artificial Intelligence and Computational Intelligence, AICI 2012, held in Chengdu, China, in October 2012. The 163 revised full papers presented were carefully reviewed and selected from 724 submissions. The papers are organized in topical sections on applications of artificial intelligence; applications of computational intelligence; data mining and knowledge discovering; evolution strategy; intelligent image processing; machine learning; neural networks; pattern recognition.