The current book shows the effects of Tranexamic acid and its derivatives; N-Phthaloyl Tranexamic acid and N-Acetyl Tranexamic acid on the metabolism and chemical modulation of glutathione in the blood and in aqueous media using UV-Visible spectrophotometer. This study also helps to understand the mechanism of action of N-Acetyl Tranexamic acid and N-Phthaloyl Tranexamic acid, in blood components.