The streets of present-day New York City are in turmoil over the ritualistic murders of a seemingly, unconnected group of residents. FBI Agent Kate Caine and her partner, Agent Mike Drake can find no clear motive, impeding her investigation. When a message is carved into the latest victim by The Night Demon, Kate consults with Dr. Emily Theodorou, curator of the Antiquities Department at the Metropolitan Museum of Art and her former lover for assistance in understanding the growing complexity of the case. Through Emily's expertise, the agents are led to mysterious woman named Lilith revealing a sinister plot of vengeance. Lilith believes she is on a mission of God but Eden, the despot of The Garden, has manipulated God's plan and has sent her to bring an unsuspecting Kate, The Chosen, to meet her undoing. A mind driven to madness through arduous travel and the constant whispers of Eden in her ear have swayed Lilith to believe that murder is the only way to force Kate's hand and persuade the dedicated Agent to heed her words. When an unbelievable act draws Kate and Emily even closer, they piece together the clues, and are captivated by where they lead - to The Garden of Eden. In her quest to solve the case, Kate follows the clues and finds herself in present day Al Basrah, Iraq and within a desolate land; once known as paradise, is now a mere memory of what it once had been. A lethal encounter with Eden and a grueling battle leads Kate to the Tree of Knowledge, its fruits still ripe. Through eating of the tree, she breaks the cycle of the curse left by Adam and Eve's transgression, bestowing upon humanity, The Garden of Eden.