Mutant Blood is the sequel to Blood Narcissus, set 20 years in the future and continuing the story of several principal characters of the earlier volume, gay vampires Dixon Pike, Sasha Mirkov, Valentin Dore, Alan Zander and Casey Beam; it also introduces several new blood-drinking immortals, including a 900-year-old Viking and a 500-year-old samurai, as well as a youthful shape-shifter.