Marco Falcone, a bright young man growing up in 1930s New York's lower East Side, dreams of becoming a doctor. But in pursuing his dream, he finds himself sucked into the La Cosa Nostra underworld, forced to provide medical services to some of the most dangerous mobsters in the city. His involvement with the mafia eventually lands him on Death Row for a crime he did not commit, left only with the hope that a lifelong friend will save him from the electric chair.