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DNA Methylation: Basic Mechanisms de Walter Doerfler

DNA Methylation: Basic Mechanisms: Current Topics in Microbiology and Immunology, cartea 301

Editat de Walter Doerfler, Petra Böhm
en Limba Engleză Paperback – 12 feb 2010
It has become apparent that the genomes of many organisms are characterized by unique patterns of DNA methylation which can differ from genome segment to genome segment and cell type to cell type. These patterns can be instrumental in determining cell type and function. Thus, it is not surprising that studies on the role of DNA methylation now occupy center stage in many fields of biology and medicine such as developmental biology, genetic imprinting, genetic disease, tumor biology, gene therapy, cloning of organisms and others. Once again, basic research in molecular biology has provided the essential foundation for investigations of biomedical problems.
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Specificații

ISBN-13: 9783642067082
ISBN-10: 3642067085
Pagini: 332
Ilustrații: VIII, 324 p. 24 illus., 6 illus. in color.
Dimensiuni: 155 x 235 x 17 mm
Ediția:Softcover reprint of hardcover 1st ed. 2006
Editura: Springer Berlin, Heidelberg
Colecția Springer
Seria Current Topics in Microbiology and Immunology

Locul publicării:Berlin, Heidelberg, Germany

Public țintă

Research

Cuprins

The Almost-Forgotten Fifth Nucleotide in DNA: An Introduction.- Pattern Formation.- Replication and Translation of Epigenetic Information.- DNA Methyltransferases: Facts, Clues, Mysteries.- DNA Methylation in Plants.- Determinant of Promoter Activity.- De Novo Methylation, Long-Term Promoter Silencing, Methylation Patterns in the Human Genome, and Consequences of Foreign DNA Insertion.- DNA Methyltransferases.- Establishment and Maintenance of DNA Methylation Patterns in Mammals.- Molecular Enzymology of Mammalian DNA Methyltransferases.- Epigenetic Phenomena.- Familial Hydatidiform Molar Pregnancy: The Germline Imprinting Defect Hypothesis?.- Dual Inheritance.- Mutagenesis and Repair.- Mutagenesis at Methylated CpG Sequences.- Cytosine Methylation and DNA Repair.

Caracteristici

Includes supplementary material: sn.pub/extras