Diabetic neuropathy is amongst the most common of the late complications of diabetes, affecting up to 50% of older patients with Type 2 diabetes. It can result in disabling neuropathic pain, lower extremity amputations and troublesome autonomic neuropathies (gastroparesis, erectile dysfunction, sudden cardiac death and so forth). With the rising incidence of diabetes the prevalence of neuropathy is also likely to increase. Over recent years, there have been new advances in our understanding and treatment of diabetic neuropathies and the problems associated with the disease.