This book constitutes the refereed proceedings of the 19th International Conference on Computing and Combinatorics, COCOON 2013, held in Hangzhou, China, in June 2013. The 56 revised full papers presented were carefully reviewed and selected from 120 submissions. There was a co-organized workshop on discrete algorithms of which 8 short papers were accepted and a workshop on computational social networks where 12 papers out of 25 submissions were accepted.