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Circadian Clocks de Achim Kramer

Circadian Clocks: Handbook of Experimental Pharmacology, cartea 217

Editat de Achim Kramer, Martha Merrow
en Limba Engleză Paperback – 16 mai 2015
This book provides the reader with a contemporary and comprehensive overview about the molecular, cellular and system-wide principles of circadian clock regulation. Emphasis is placed on the importance of circadian clocks for the timing of therapeutic interventions.
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Specificații

ISBN-13: 9783642448539
ISBN-10: 3642448534
Pagini: 428
Ilustrații: X, 417 p.
Dimensiuni: 155 x 235 x 24 mm
Greutate: 0.65 kg
Ediția:2013
Editura: Springer
Colecția Handbook of Experimental Pharmacology
Seria Handbook of Experimental Pharmacology

Locul publicării:Berlin, Heidelberg, Germany

Cuprins

Part I. Molecular and cellular basis of circadian clocks. Molecular components of the mammalian circadian clock. The epigenetic language of circadian clocks. Peripheral circadian oscillators in mammals. Cellular mechanisms of circadian pacemaking: beyond transcriptional loops. The clock in the brain: Neurons, glia and networks in daily rhythms.- Part II. Circadian control of physiology and behavior. Circadian clocks and metabolism. The circadian control of sleep. Daily regulation of hormone profiles. Circadian clocks and mood-related behaviors. Part III. Chronopharmacology and chronotherapy. Molecular Clocks in Pharmacology. Cancer chronotherapeutics: Experimental, theoretical and clinical aspects. Pharmacological modulators of the circadian clock as potential therapeutic drugs: Focus on genotoxic/anticancer therapy. Light and the human circadian clock.- Part IV. Systems biology of circadian clocks. Mathematical modeling in chronobiology. Mammalian circadian clock: the roles of transcriptional repression and delay. Genome-wide analyses of circadian systems. Proteomic approaches in circadian biology.

Caracteristici

A timely book about the widespread impact of circadian clocks For a broad readership in both basic science but also translational and clinical medicine Written by leading authorities in the field Includes supplementary material: sn.pub/extras