Cantitate/Preț
Produs
Total produse
Vezi coșul
Cardiovascular Solid Mechanics de Jay D. Humphrey

Cardiovascular Solid Mechanics

Autor Jay D. Humphrey
en Limba Engleză Hardback – 8 ian 2002

În domeniul ingineriei biomedicale și al biotehnologiei, înțelegerea funcționării sistemului cardiovascular necesită o analiză riguroasă a interacțiunilor mecanice la nivel de celule, țesuturi și organe. În Cardiovascular Solid Mechanics, autorul Jay D. Humphrey oferă o sinteză tehnică a modului în care inima și arterele răspund la stimuli mecanici, utilizând instrumentele avansate ale mecanicii neliniare a solidelor. Remarcăm faptul că această lucrare nu se limitează la o descriere calitativă, ci impune o rigoare matematică necesară pentru rezolvarea problemelor de valoare la limită și inițiale, specifice condițiilor in vivo. Structura volumului reflectă o progresie logică, pornind de la preliminarii matematice și calcul tensorial, continuând cu mecanica continuumului și elasticitatea finită, pentru a culmina cu metodele experimentale de măsurare a deformării și estimare a parametrilor. Cititorul care a aplicat ideile din Biomechanics of Soft Tissue in Cardiovascular Systems de Gerhard A. Holzapfel va găsi aici o aprofundare a integrării metodelor computaționale cu cele experimentale, oferind un cadru mai vast pentru modelarea constitutivă a țesuturilor moi. Poziționată strategic în cadrul operei autorului, această carte extinde conceptele fundamentale prezentate în An Introduction to Biomechanics, trecând de la principiile generale de echilibru și stres către aplicații complexe în mecanobiologie. Considerăm că forța acestui text rezidă în capacitatea de a unifica teoria cu practica de laborator, oferind studenților și cercetătorilor un ghid metodologic pentru analiza neliniarităților geometrice și de material inerente sistemului vascular. Deși focusul principal rămâne cel cardiovascular, metodele analitice prezentate de Jay D. Humphrey sunt direct transferabile către studiul altor tipuri de țesuturi biologice moi.

Citește tot Restrânge

Preț: 97864 lei

Preț vechi: 119346 lei
-18%

Puncte Express: 1468
Paperback 97303 lei
Hardback 97864 lei

Carte tipărită la comandă

Livrare economică 09-23 noiembrie

Livrare prin curier în România Termenul estimat este afișat lângă disponibilitate.
Transport gratuit pentru acest produs Plată online sau ramburs, în funcție de opțiunile comenzii.
Retur gratuit în 14 zile Comandă securizată și suport în română.
 Adaugă în coș

Wish list
Gift list
Am citit!
Adaugă în listă

Specificații

ISBN-13: 9780387951683
ISBN-10: 0387951687
Pagini: 776
Ilustrații: XVI, 758 p.
Dimensiuni: 160 x 241 x 46 mm
Greutate: 1.23 kg
Ediția:2002
Editura: Springer
Locul publicării:New York, NY, United States

Public țintă

Graduate

De ce să citești această carte

Această lucrare este esențială pentru cercetătorii și studenții de la facultățile de bioinginerie care doresc să stăpânească modelarea matematică a inimii și a vaselor de sânge. Cititorul câștigă o înțelegere profundă a mecanicii neliniare și a metodelor experimentale riguroase. Este un instrument practic pentru cei care urmăresc să dezvolte simulări computaționale precise sau să interpreteze date experimentale complexe în contextul biomecanicii țesuturilor moi.

Descriere scurtă

This text presents a general introduction to soft tissue biomechanics. One of its primary goals is to introduce basic analytical, experimental and computational methods. In doing so, it enables readers to gain a relatively complete understanding of the biomechanics of the heart and vasculature.

Descriere

The vitality of the cardiovascular system, which consists of the heart, vas­ culature, and blood, depends on its response to a host of complex stimuli, including biological, chemical, electrical, mechanical, and thermal. The focus of this book, however, is on the response of the heart and arteries to mechanical loads from the perspective of nonlinear solid mechanics. Through my own research in this field, I have come to realize that study­ ing the complex responses of cardiovascular cells, tissues, and organs nec­ essarily requires a combined theoretical, experimental, and computational approach. Theory is needed to guide the performance and interpretation of experiments as well as to synthesize the results; experiment is needed to study the responses of the system to well-controlled loads and to test can­ didate hypotheses and theories; and due to the geometric and material non­ linearities inherent to cardiovascular mechanics, computation is needed to analyze data as well as to solve boundary and initial value problems that correspond to either experimental or in vivo conditions. One of the primary goals of this book is to introduce together basic analytical, experimental, and computational methods and to illustrate how these methods can and must be integrated to gain a more complete understanding of the bio­ mechanics of the heart and vasculature. Despite the focus on cardiovascu­ lar mechanics, the fundamental methods, indeed many of the specific results, are generally applicable to many different soft tissues.

Cuprins

1. INTRODUCTION.1.1 Historical Prelude, 1.2 Basic Cell Biology, 1.3 The Extracellular Matrix, 1.4 Soft Tissue Behavior, 1.5 Needs and General Approach, 1.6 Exercises, 1.7 References.2. MATHEMATICAL PRELIMINARIES2.1 A Direct Tensor Notation, 2.2 Cartesian Components, 2.3 Further Results in Tensor Calculus, 2.4 Orthogonal Curvilinear Components, 2.5 Matrix Methods, 2.6 Exercises, 2.7 References,3. CONTINUUM MECHANICS3.1 Kinematics, 3.2 Forces, Tractions and Stresses, 3.3 Balance Relations, 3.4 Constitutive Formulations, 3.5 Boundary and Initial Conditions, 3.6 Exercises, 3.7 References,4. FINITE ELASTICITY4.1 Introduction, 4.2 Incompressible Isotropic Elasticity, 4.3 Solutions in 3-D Incompressible Elasticity, 4.4 Compressible Isotropic Elasticity, 4.5 Membrane Hyperelasticity, 4.6 Exercises, 4.7 References5. EXPERIMENTAL METHODS5.1 General Philosophy, 5.2 Measurement of Strain, 5.3 Measurement of Applied Loads, 5.4 Testing Conditions, 5.5 Parameter Estimation and Statistics, 5.6 Exercises, 5.7 References6. Finite Element Methods6.1 Fundamental Equations, 6.2 Interpolation, Integration, and Solvers, 6.3 An Illustrative Formulation, 6.4 Inflation of a Membrane, 6.5 Inverse Finite Elements, 6.6 Exercises, 6.7 ReferencesPART II - VASCULAR MECHANICS7. THE NORMAL ARTERIAL WALL7.1 Structure and Function, 7.2 General Characteristics, 7.3 Constitutive Framework, 7.4 Experimental Methods, 7.5 Specific Constitutive Relations, 7.6 Stress Analyses, 7.7 Exercises, 7.8 References8. VASCULAR DISORDERS8.1 Hypertension, 8.2 Intracranial Aneurysms, 8.3 Atherosclerosis, 8.4 Aortic Aneurysms, 8.5 Additional Topics, 8.6 Exercises, 8.7 References9. VASCULAR ADAPTATION9.1 Mechanical Preliminaries, 9.2 Cellular Responses to Applied Loads, 9.3 Arterial Response to Hypertension, 9.4 Arterial Response to Altered Flow, 9.5 Vessel Response to Injury, 9.6 Veins as Arterial Grafts, 9.7 Aging, 9.8 Exercises, 9.9 ReferencesPART III CARDIAC MECHANICS10. THE NORMAL HEART10.1 Structure and Function, 10.2 General Characteristics, 10.3 Constitutive Framework, 10.4 Constitutive Relations, 10.5 Stress Analyses, 10.6 Exercises, 10.7 References11. EPILOGUEAPPENDICESI. Nomenclature, Abbreviations, and ConversionsII. Results for Curvilinear CoordinatesIII. Material Frame Indifference11. CARDIAC DISORDERS11.1 Ischemia 11.2 Volume Overload11.3 Hypertrophy 11.4 Cardiac Aneurysms11.5 Additional Topics

Notă biografică

Jay D. Humphrey is a John C. Malone Professor of Biomedical Engineering at Yale University. He received the Ph.D. degree in Engineering Science and Mechanics from The Georgia Institute of Technology and completed a post-doctoral fellowship in Cardiovascular Research at The Johns Hopkins University. He has authored a book titled Cardiovascular Solid Mechanics: Cells, Tissues, and Organs, co-authored a book titled Style and Ethics of Communication in Science and Engineering, co-edited a book titled Cardiovascular Soft Tissue Mechanics, and authored or co-authored chapters for over 20 other books or encyclopedias as well as over 200 archival technical papers. He served as founding co-Editor In Chief for the international journal Biomechanics and Modeling in Mechanobiology and has served as Associate Editor for five other technical journals. He is a Fellow of the American Society of Mechanical Engineers (Bioengineering Division) and the American Institute of Medical and Biological Engineers. Sherry L. O'Rourke is a Technical Field Engineer at Medtronic Inc. in the Cardiac Rhythm Disease Management Division. She received the B.S. and M.S. degrees in Biomedical Engineering from Texas A&M University and co-authored an archival paper on the biomechanics of the lens capsule of the eye, which is important in understanding device design for cataract surgery. Since graduation she has spent her professional life dedicated to designing, developing, and teaching programs to help physicians, residents, and nurses ensure that patients receive the maximum benefit from pacemakers and implantable defibrillators that are designed for those suffering from chronic heart disease.