1.ACCESSING BIBLIOGRAPHIC DATABASE FROM NCBI 2.RETRIEVING PROTEIN / NUCLEOTIDE SEQUENCE INFORMATION FROM NCBI DATABASE 3.RESTRICTION MAPPING 4.SIMILARITY SEARCH USING FASTA TOOL FROM EMBL 5.SIMILARITY SEARCH USING BLAST TOOL FROM NCBI 6.PAIRWISE SEQUENCE ALIGNEMENT -EMBOSS SUITE 7.MULTIPLE SEQUENCE ALIGNMENT - CLUSTAL OMEGA 8.EVOLUTIONALRY RELATIONSHIP- PHYLOGENETIC ANALYSIS - TREE VIEW 9.PDB RETRIEVING 10.MOLECULAR VISUALIZATION-RASMOL 11.IDENTIFICATION OF GENE (HMGA2) IN HUMAN GENOME & Primer Designing 12.INTRODUCTION TO AUTODOCK 13.CALCULATION OF SD, VARIANCE, GRAPH PLOT - MS EXCEL 14.OPEN READING FRAME FROM - NCBI 15.RAMACHANDRAN PLOT