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Bayesian Adaptive Design for Immunotherapy and Targeted Therapy de Haitao Pan

Bayesian Adaptive Design for Immunotherapy and Targeted Therapy

Autor Haitao Pan, Ying Yuan
en Limba Engleză Paperback – 21 apr 2024
This book provides a comprehensive review of novel adaptive trial designs for targeted therapies and immunotherapies. This book covers a wide range of novel statistical designs for various clinical settings, including early phase dose-escalation study, proof-of-concept trials, and confirmatory studies with registrational. The book includes real-life examples and software to facilitate practitioners to learn and use the designs in practice.
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Specificații

ISBN-13: 9789811984679
ISBN-10: 9811984670
Pagini: 262
Ilustrații: XI, 262 p. 58 illus., 50 illus. in color.
Dimensiuni: 155 x 235 mm
Ediția:2023
Editura: Springer Nature Singapore
Colecția Springer
Locul publicării:Singapore, Singapore

Cuprins

Introduction to Adaptive Design and Delayed Outcomes.- Basics of Bayesian Statistics.- Phase I Dose-finding Design.- Phase II Design for Interim Monitoring.- Phase I-II Dose-finding Design.- Drug Combination Trial Design.- Conclusion.

Textul de pe ultima copertă

This book provides a comprehensive review of novel adaptive trial designs for targeted therapies and immunotherapies. This book covers a wide range of novel statistical designs for various clinical settings, including early phase dose-escalation study, proof-of-concept trials, and confirmatory studies with registrational. The book includes real-life examples and software to facilitate practitioners to learn and use the designs in practice.

Caracteristici

The first book focusing on novel adaptive designs for targeted and immunotherapies Comprehensive coverage of state-of-the-art Bayesian adaptive designs, such as model-assisted designs Including many real-world trial examples