Nuclear medicine has become an ever-changing and expanding diagnostic and therapeutic medical profession. The day-to-day innovations seen in the field are, in great part, due to the integration of many scientific bases with complex technologic advances. The aim of this reference book, Basic Sciences of Nuclear Medicine, is to provide the reader with a comprehensive and detailed discussion of the scientific bases of nuclear medicine, covering the different topics and concepts that underlie many of the investigations and procedures performed in the field. Topics include radiation and nuclear physics, Tc-99m chemistry, single-photon radiopharmaceuticals and PET chemistry, radiobiology and radiation dosimetry, image processing, image reconstruction, quantitative SPECT imaging, quantitative cardiac SPECT, small animal imaging (including multimodality hybrid imaging, e.g., PET/CT, SPECT/CT, and PET/MRI), compartmental modeling, and tracer kinetics.