This report documents the findings of a special study undertaken to update, confirm and expand upon previous studies on the comparative (to experienced carriers) safety performance and compliance of large commercial motor vehicle operators (motor carriers) newly entering into U.S. interstate operations. Once these operator/carriers engage in interstate operations with large commercial motor vehicles, they are required to register with the U.S. Department of Transportation (USDOT) and they become subject to the Federal Motor Carrier Safety Regulations (FMCSRs). In particular, this study was accomplished to help provide a basis for formulating the details of a new entrant education and safety assurance process including the possible need for special emphasis among the component groups of new entrants. Component groups include U.S., Canadian, and Mexican domiciled motor carriers newly registering with the USDOT for interstate operations in the U.S..