Allergic Disease Models
Editat de José de la Fuente, Alejandro Cabezas-Cruzen Limba Engleză Hardback – 16 noi 2026
This detailed volume provides a comprehensive and protocol-driven resource covering the entire spectrum of experimental models and translational applications for allergic diseases. The book integrates cutting-edge in vivo models, such as mice, pigs, zebrafish, dogs, and sheep, novel models for tick-borne allergies and Alpha-Gal syndrome, microbiota-based protocols, multiomics integration workflows, bioinformatics pipelines, and clinical diagnostic methods. These methods provide tools for advancing in the study of allergic diseases and the development of diagnostic, preventive, and therapeutic interventions. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.
Authoritative and practical, Allergic Disease Models: Methods and Translational Protocols serves as an ideal guide to validated methods for accelerating research, clinical applications, and biomarker discovery in allergic disease research.
Preț: 1597.89 lei
Preț vechi: 1681.98 lei
-5% Precomandă
Carte nepublicată încă
Specificații
Cuprins
Introduction to Allergy Modeling Across Species with Ethical and Regulatory Considerations.- Guidelines to Apply for Ethical Approval of Animal Experimentation and Use of Human Samples.- Artificial Feeding of Hard Ticks Using Silicone Membranes.- Tick Saliva Collection.- The Zebrafish Model for Alpha-Gal Syndrome.- The Humanized Mouse Model of AGS: A Preclinical System for Analyzing Hypersensitivity to α-Gal and Potential Allergenic Epitopes.- Proteomics Analysis for Discovery of Biomarker of Tick Allergy.- Analysis of Metabolomics Response to Tick Saliva in Human Cells.- Protective Pathogen Infection Against Tick Induced¿Allergy in¿Zebrafish.- Flow Cytometry in Human Cells Exposed to Tick Salivary Proteins.- Evaluation of Alpha-Gal Content and Expression of Galactosyltransferases in Arthropods.- Untargeted UHPLC–HRMS Lipidomic Profiling of Ticks for Alpha-Gal Syndrome Research.- Predictive Functional Profiling of Allergy-Associated Microbiota with¿PICRUSt2.- Experimental Food Allergy: From Induction to Anaphylaxis Assessment in a Rat Model.- Integrative Analysis of Gut Microbiota in Alpha-Gal Research.- Experimental Model to Study Microbiota Perturbation Role in Alpha-Gal Syndrome.- Integration of Multiomics Datasets to Identify Allergy Biomarkers and Protective Signatures.- Modeling Antigen Allergenicity with Bioinformatics Approaches.- Participatory Citizen Science to Evaluate Risks and Interventions to Allergic Reactions to Arthropod Bites.- ImmunoCAP-Based Detection of Alpha-Gal Syndrome: A Reproducible Diagnostic Protocol for Human Patients.- Protocols for Diagnosis and Management of Arthropod Bite Allergies in Humans.- Genotyping Protocol for Identifying Genetic Risk Markers Associated with Alpha-Gal Syndrome.- Clinical Protocol for Evaluating Ectoparasite-Induced Allergies with Emphasis on Alpha-Gal Syndrome.- Protocol for the Manipulation of Fossil Amber to Reduce Allergenic Effects.