In After Delores, the unnamed narrator is a no-nonsense coffee shop waitress in New York's bohemian Lower East Side nursing a broken heart after her girlfriend Dolores leaves her for another woman. Over the course of the next few days she goes on the prowl, looking for love, only to find herself immersed in a tangled web of seduction, deceit and murder. Along the way she meets a diverse array of characters, from hot femme Priscilla, go-go dancer Punkette and bewitching and brutal actress Charlotte.