This book explores the intersection of molecular biology, genomics, and ecology to redefine our understanding of parasitic organisms and their management. Beginning with the application of -omics research in platyhelminth parasites of fish, demonstrating how genomic and proteomic data are essential for understanding host-parasite dynamics and developing novel vaccines and treatments to support sustainable aquaculture. The focus then shifts to the complex internal ecosystems of parasites, and examining how their associated microbiomes—comprising bacteria, fungi, and viruses—influence parasite fitness, virulence, and host interactions. Finally, the book highlights the genus Entamoeba, delving into how how next-generation and long-read sequencing technologies have revolutionized the identification of cryptic species and improved epidemiological surveillance for pathogens like E. histolytica. Together, these chapters provide a modern framework for parasitology through the lens of advanced genetic tools and ecological integration.

• · Direct application to global food security
  · Integration of the "holobiont" concept
  · Genetics-based redefinition of parasite taxonomy