In this issue of Clinics in Plastic Surgery, guest editors Drs. Francesco M. Egro and C. Scott Hultman bring their considerable expertise to the topic of Acute and Reconstructive Burn Care, Part I. Top experts in the field discuss topics relevant to this complex field, including timing of excision/grafting and burn reconstruction; sedation and pain management in adult and pediatric patients; how to minimize narcotic use; critical care, ethical issues, and palliative care; and much more.