This book focus on 15 essential clinical trial practices which must be followed by an Investigator. These 15 practices have been divided into 3 phases: Before Initiating a Trial, During Conduction of Trial and After Completion or Termination of Trial. The book covers essential elements which investigator needs to follow in a trial like: Contracts and Agreements, Constitution and Training of Study Team, Procurement of Equipment's, Compliance, Medical Care and Protection of Study Subjects, Recruitment, Recording Data, IP Accountability, SAE Reporting, Documentations, Data Verification, Communication, Financial Tracking, Archival etc.