Raised in England and living in New York, Emilio Winters and Karl Deadshore funded by Emilio's rich stockbroker father travel down to Lima Peru for a vacation. Unbeknownst to Karl Emilio has an ulterior motive, which involves travelling deep into the Amazon rainforest to find a plant which he believes holds the key to a legitimate clean cure for cancer. Lost while struggling their way through the jungle they meet a mysterious young women named Valencia Dru who promises to help get them back on track. But events get out of hand and their predicament quickly snowballs into a nightmare worse than any of them could have ever imagined.