What Do I Do Now? is a memoir in the form of 100 essays and anecdotes. The book describes the author's response to his wife of over 30 years declining with Alzheimer's. It tracks the emotional, psychological, and spiritual ups and downs during the anticipatory grief process. It is at the same time an inspirational guide to coping with difficulties in life and growing stronger through the experience. The book contains both raw emotions and philosophical insights. The book articulates issues that are often difficult to express or considered embarrassing, such as the end of sex, incontinence, and behavioral problems. It includes material derived from Twelve Step programs, A Course in Miracles, and Buddhist meditation practice.