Alison embarks on her first experience as a sleep therapist as she travels to Elloree, South Carolina. She has taken on a job at the old hospital now converted to a sleep lab that helps people who suffer from insomnia. Alison excited about her new life and career makes the fatal mistake of breaking the one rule, "DO NOT ENTER ROOM 13." Peeking into the forbidden room Alison is taken on a journey she may never wake from. The girl Alison sees in room 13 starts the twists and nightmares. Alison starts to suffer from night terrors, insomnia, and migranes as she forces herself to stay away from the forbidden room. Alison dreams of Kelly the girl behind the door. Kelly had died in the old hospital after years of trauma, missing friends, and self mutulation. Kelly left alone for years in the room, suffering from nightmares of friends and family that disappeared. Her twin brother dying on deathrow convicted of murdering their roommates. But did he do the crime? Alison struggles to erase the visit to the room, but the pull to the room takes over her life. Alison finally gives in and returns to the room, the place where it all started.