The future of precision health care is being driven by the increasingly rapid evolution of technologies. Over the past century, health care has benefited tremendously from the steady introduction of new tools, such as imaging, vaccines, immunology, biochemical analysis, and drug development; more recently, emerging technologies have arisen rapidly, undergone swift validation, and experienced prompt application. However, these technologies and their results have uncertainties and impact all facets of precision patient management. Uncertain Precision: Managing Health Care with Personalized Technologies provides an in-depth overview of precision medicine and its relationship with new technology, examining its current scope, benefits, and limitations. While new medical technologies can identify many individual traits that establish diagnoses, predict the course of illness, and recommend therapies, the tools and their results have uncertainties that the health care professional must anticipate and recognize. Utilizing clinical examples from his own experience and insights from colleagues and other experts, Dr. Reed E. Pyeritz discusses key technologies, such as genome sequencing, artificial intelligence, targeting a patient's immune cells to cancer, and gene therapies. Timely and compelling, Uncertain Precision is an essential resource for anyone interested in the future of health care and the role of precision medicine in delivering tailored medical solutions.