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Toxoplasma Gondii: The Model Apicomplexan - Perspectives and Methods

Editat de Louis M. Weiss, Kami Kim
en Limba Engleză Hardback – 2027
Toxoplasma Gondii: The Model Apicomplexan - Perspectives and Methods, Fourth Edition offers a comprehensive approach and balance between historical research, new developments, and innovative approaches to Toxoplasma gondii research. Completely updated and revised, the new Edition aims to provide a better understanding of the structure, genetic diversity, and population biology of T. gondii. The book details the immunology, molecular, and cellular biology of Toxoplasma gondii combined with new molecular techniques, methods, and resources for working with this pathogen. It also offers the latest information concerning epidemiology, diagnosis, treatment, and prevention of toxoplasmosis.

With contributions from leading experts in the field, this is an essential one-stop resource for a wide range of researchers, scientists, and clinicians engaged in the study of T. gondii and toxoplasmosis.

  • Offers contributions from leading experts in the field, including new topics such as One Health and toxoplasmosis in wild and domestic animals, secreted effectors and host cell manipulation, Cryo-electron microscopy (CryoEM), and the identification of subcellular proteome using hyperLOPIT
  • Includes new information on the ultrastructure, genomics, epigenomics, and proteomics of T. gondii genomics
  • Provides expanded information on the effects of T. gondii and the implication of toxoplasmosis on neurological diseases and psychiatric diseases
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Specificații

ISBN-13: 9780443450488
ISBN-10: 044345048X
Pagini: 1000
Dimensiuni: 191 x 235 mm
Ediția:4
Editura: ELSEVIER SCIENCE

Cuprins

Preface
1. The history and life cycle of Toxoplasma gondii
2. The ultrastructure of Toxoplasma gondii
3. Cryo-EM to define the Toxoplasma gondii conoid and other structures
4. Molecular epidemiology and population structure of Toxoplasma gondii
5. Human Toxoplasma infection
6. Ocular disease due to Toxoplasma gondii
7. Toxoplasma gondii as a model for One Health
8. Toxoplasma animal models and therapeutics
9. Toxoplasma gondii: lipid synthesis and uptake and host cell interactions
10. Metabolic networks and metabolomics
11. The Apicoplast and Mitochondrion of Toxoplasma gondii
12. Calcium and cyclic nucleotide signaling networks in Toxoplasma gondii
13. Toxoplasma secretory proteins and their roles in parasite cell cycle and infection
14. Endomembrane trafficking pathways in Toxoplasma
15. The Toxoplasma cytoskeleton: structures, proteins, and processes
16. Effectors Produced by Rhoptries and Dense Granules: An Intense Conversation Between Parasite and Host in Many Languages
17. Bradyzoite and sexual stage development in Toxoplasma gondii
18. Development and application of classical genetics in Toxoplasma gondii
19. Genetic manipulation of Toxoplasma gondii
20. Regulation of gene expression in Toxoplasma gondii
21. Proteomics and Post Translational Modifications in Toxoplasma gondii
22. Cerebral toxoplasmosis
23. Innate immunity to Toxoplasma gondii
24. Adaptive immunity
Appendix A
Appendix B
Epilogue