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Total Intravenous Anesthesia and Target Controlled Infusions de Anthony R. Absalom

Total Intravenous Anesthesia and Target Controlled Infusions

Editat de Anthony R. Absalom, Keira P. Mason
en Limba Engleză Hardback – 10 mar 2017

Gestionarea profunzimii anestezice și predictibilitatea recuperării postoperatorii rămân provocări constante în practica modernă, unde trecerea de la anestezia inhalatorie la tehnicile intravenoase necesită o înțelegere riguroasă a cineticii medicamentelor. Observăm cum Total Intravenous Anesthesia and Target Controlled Infusions, sub coordonarea editorilor Anthony R. Absalom și Keira P. Mason, reușește să sintetizeze această complexitate într-o antologie globală de referință. Manual de referință comparabil cu Taking on TIVA, dar actualizat conform ghidurilor și progreselor tehnologice din 2017, volumul de față depășește abordarea pur procedurală, oferind fundamentul științific necesar pentru utilizarea sistemelor TCI (Target Controlled Infusion). Structura lucrării este logică și progresivă: începe cu mecanismele neurobiologice ale conștienței și acțiunii anestezicelor, trece prin principiile matematice ale modelării farmacocinetice și farmacodinamice (PK/PD) și culminează cu aplicațiile clinice practice. Ne-a atras atenția rigoarea cu care sunt tratate capitolele dedicate selecției modelelor PK/PD, un aspect critic pentru evitarea supradozării sau a trezirii intraoperatorii. Față de On the Study and Practice of Intravenous Anaesthesia, care punea bazele utilizării computerizate, această ediție publicată de Springer integrează date despre agenți mai recenți, precum Dexmedetomidina, și explorează managementul blocantelor neuromusculare în contextul TIVA. Este o resursă care nu doar descrie tehnica, ci analizează critic studiile de outcome, oferind o perspectivă nuanțată asupra siguranței pacientului și eficienței clinice în sala de operație.

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Specificații

ISBN-13: 9783319476070
ISBN-10: 3319476076
Pagini: 844
Ilustrații: XVIII, 824 p. 324 illus., 200 illus. in color. With online files/update.
Dimensiuni: 215 x 285 x 48 mm
Greutate: 2.52 kg
Ediția:1st ed. 2017
Editura: Springer
Locul publicării:Cham, Switzerland

De ce să citești această carte

Această lucrare se adresează medicilor anesteziști care doresc să treacă de la o practică empirică a anesteziei intravenoase la una bazată pe modelare farmacologică precisă. Cititorul câștigă expertiză în configurarea sistemelor TCI și înțelegerea nuanțată a interacțiunilor dintre propofol și opioide. Este un instrument esențial pentru cadrele universitare care doresc să implementeze un curriculum modern de TIVA în programele de rezidențiat.

Despre autor

Anthony R. Absalom este un nume de referință în anesteziologia internațională, cunoscut pentru cercetările sale aprofundate în farmacologia clinică și sistemele de infuzie controlată. Alături de Keira P. Mason, expertă recunoscută în anestezia pediatrică și sedarea în afara sălii de operație, au reușit să mobilizeze o rețea globală de specialiști pentru a crea acest manual. Expertiza lor combinată asigură echilibrul între rigoarea academică a modelării matematice și necesitățile pragmatice ale clinicianului care se confruntă cu cazuri complexe în terapie intensivă sau blocul operator.

Descriere scurtă

This is a comprehensive and authoritative presentation of total intravenous anesthesia (TIVA) and target controlled infusion (TCI). The editors’ international reputation has enabled them to recruit leading experts from around the world to write single-author chapters in their area of expertise. Total Intravenous Anesthesia and Target Controlled Infusions is the first multi-disciplinary, globally authored volume on the topic.  

Providing a single source of information on all aspects of TIVA and TCI, from pharmacologic modeling and the pharmacology of intravenous anesthetic drugs to practical considerations in the clinical setting and the requirements of special populations, Total Intravenous Anesthesia and Target Controlled Infusions examines the debate about the risks and advantages of TIVA, analyze outcome studies, and provides guidance on creating a curriculum to teach TIVA and TCI.

Cuprins

PART 1.  INTRODUCTION/BACKGROUND.- 1. When and How Did It All Begin? A Brief History of Intravenous Anesthesia.- 2. The Development and Regulation of Commercial Devices for Target - Controlled Drug Infusion.- 3. The Memory Labyrinth: systems, processes and boundaries.- 4. Consciousness and Anaesthesia.- 5. Mechanisms of Intravenous Anaesthetic Action.- PART 2.  PRINCIPLES OF PHARMACOLOGICAL MODELING.- 6. Basic Pharmacology: Kinetics and Dynamics for Dummies.- 7. Pharmacokinetic-Pharmacodynamic Modelling of Anesthetic Drugs.- 8. Principles of Target Controlled Infusions.- 9.  Performance of Target-Controlled Infusion Systems.- 10. How to Select a PK/PD Model.- PART 3.  PHARMACOLOGY OF THE INTRAVENOUS ANESTHETIC AGENTS.- 11. Propofol PK-PD.- 12. Etomidate and Etomidate Analogues: Molecular Pharmacology and Behavioral Actions.- 13. Dexmedetomidine: The Science and Clinical Aspects in Adults and Children.- 14. Clinical Effects and Applications of Ketamine.- 15. Neuromuscular Blocking Drugs: Pharmacology, Physiology and Clinical Aspects.- 16. New and Upcoming Drugs: Intravenous Anesthetic Agents.- 17. Drug Interactions in Anesthesia.- PART 4. PRACTICAL CONDUCT OF SEDATION AND ANESTHESIA
18. Pumps Pitfalls and Practicalities.- 19. EEG Monitoring of Depth of Anesthesia.- 20. Monitoring the analgesic component of anesthesia.- 21. Intravenous Drugs for Sedation: Target Controlled, Patient Controlled, and Patient Maintained Delivery.- 22. Pediatric TIVA/TCI: Case Presentations and Discussion.- 23. TCI/TIVA Adult Case Studies.- PART 5. SPECIAL POPULATIONS AND PROCEDURES.- 24. Intravenous Anesthesia in Obese Patients.- 25. Pharmacokinetics and Dynamics on the Pediatric Population.- 26. Clinical Pharmacology of Intravenous Sedation in Children.- 27. Sedation of the Critically Ill Child.- 28. TCI & TIVA for Neurosurgery: Considerations and Techniques.- 29. TCI in Special Patients Groups: The Elderly and Obese.- 30. TIVA for Cardiac Surgery.-31. TIVA/TCI in Veterinary Practice.- PART 6. OUTCOME, EDUCATION, SAFETY, AND THE FUTURE.- 32. Advantages, Disadvantages, and Risks of TIVA/TCI.- 33. Economics of TIVA.- 34. Teaching TCI with Human Patient Simulators.- 35. Closed-Loop or Automated Titration of Intravenous Anesthesia: Background, Science and Clinical Impact.- 36. Health Care Technology, the Human-Machine Interface, and Patient Safety During Intravenous Anesthesia.- 37.  Can IV Sedatives Affect Outcome?.- 38. The Benefit and Future of Pharmacogenetics.- 39. Lessons from drug interaction displays.- 40. The Role of Intravenous Agents in Delirium.- 41. Perioperative Cardioprotective Strategies in Noncardiac Surgery.- 42. Opioid Induced Hyperalgesia after Surgery: Clinical Relevance.- 43. Memory, Awareness and Intravenous Anaesthetics.- 44. Awareness and Dreaming During TIVA.- 45. Apoptosis and Neurocognitive Effects of Intravenous Anesthetics.- Epilogues.

Recenzii

“Total Intravenous Anesthesia and Target Controlled Infusions is a traditional textbook that bills itself as a comprehensive guide to the subject. … this textbook form part of the reference collection of all anesthetic department libraries. It is a high-quality volume, well bound with excellent color illustrations, printed on thick paper, and is a worthwhile purchase. … Those that take the time to read a good portion of it will be richly rewarded in their increased understanding of TIVA.” (Timothy G. Short and Gerard Willemsen, Anestesia & Analgesia, Vol. 125 (1), January, 2018)

Notă biografică

Anthony  R. Absalom, MBChB, FRCA, MD
Professor of Anesthesiology, The University Medical Center Groningen, University of Groningen, The Netherlands
Dr. Absalom is internationally recognized as a leading expert on anaesthetic pharmacology and total intravenous anesthesia. He currently serves as Editor of the British Journal of Anaesthesia and is a former editorial board member of Trends in Anaesthesia and Critical Care.  He is currently president of the Society for Intravenous Anesthesia (UK). In the past he has served as a board member of ISAP (International Society for Intravenous Anaesthesia) and as vice-president of the World Society of Intravenous Anaesthesia. 

Keira P. Mason, MD is an Associate Professor of Anaesthesia (Radiology) at Harvard Medical School, , Boston Children’s Hospital, Boston, MA. 
Dr. Mason is a Springer author.  We recently published the expanded Second Edition of her critically and globally acclaimed book, Pediatric Sedation Outside of the Operating Room, 2nd ed, Mason, ed., (2015).  
During 1998-2014, Dr. Mason was Director of Radiology Anesthesia and Sedation at Boston Children’s Hospital, where she developed a sedation and anesthesia program that continues to be nationally and internationally recognized.  She is considered a pioneer of innovative and safe sedation protocols which have been adopted worldwide.  Dr. Mason is past- Vice President of the World Society of Intravenous Anesthesia (Founding Board Member), and a frequent invited lecturer to national and international conferences, including Society of Interventional Radiology, American Society of Anesthesiologists, Radiological Society of North America, International Dental Congress on Anesthesia, Sedation, and Pain Control, Society of Ambulatory Anesthesia, Asian and Oceanic Society of Regional Anesthesia, Japanese Society for Intravenous Anesthesia, International Association of Pediatric Dentistry, All-African Anaesthesia Congress, Asian Society of Paediatric Anesthesiologists, and many others. She is the Course Director for Pediatric Sedation Outside the Operating Room, a conference she initiated through Harvard Medical School and is an active member of the American Society of Anesthesiologists (ASA) Committees. She has authored many book chapters.  As a Principal Investigator of numerous studies, some which required approval of the Food and Drug Administration (FDA), she has numerous publications. Dr. Mason continues to serve on expert panels for the FDA.  She is on the Editorial Board of the British Journal of Anaesthesia.

Caracteristici

First definitive text of total intravenous anesthesia and target controlled infusion Internationally renowned editors and contributors provide comprehensive, expert coverage Addresses history of TIVA and of TCI, neuropharmacology of TIVA, and pharmacological modeling basics In-depth profiles of drugs used in TIVA and of up-and-coming new drugs Drug interactions Case studies of adult and pediatric patients, with accompanying video Risks and benefits, outcomes, training, and patient safety also addressed Includes supplementary material: sn.pub/extras