Though the skill & technique of the surgeon are important for wound healing, so is the choice of suture materials. The choice of an appropriate suture for any wound closure will make a large contribution to the final functional & cosmetic result. An histological comparison of sutures is provided here to give readers a full understanding of wound healing when different types of suture materials are used. We sincerely hope that surgeons past, present & future will benefit from this research & thus treat their patients successfully.