On vacation in New Orleans in 2016, newlyweds Luke and Jamie Bowden visit a voodoo museum, where a voodoo witch sends them on a mission back to the year 1794. Landing in the colonial city during a fire that razed most of the town, they meet and become indispensible to Don Andres Almonester, Chevalier of the Royal Order of King Charles III of Spain. Louisiana is still a colony, then under Spanish Domination. Jamie, a trained nurse and considered a miracle worker by the Almonesters for performing the most basic 21st Century medical procedures, is pressed into service by the Don's wife, who is expecting her first baby.. Jamie and Luke's adventures in trying to complete the mission given them, keep the good favor of Don Almonester, and find a way back to the 21st Century, bring them to the center of terrifying voodoo rituals, from which only their courage and ingenuity can save them."