When newspaperman Jim Locke's estranged sister, a wealthy actress, is murdered, the police name him as their primary suspect. The lead detective on the case, Michael Boyle, has a shady reputation and appears willing to do anything to prove Jim guilty. Determined to clear his name, Jim soon discovers evidence connecting his sister and several other murdered actresses to Doctor Henry Greeley. Greeley is a war hero and a respected psychiatrist who is obsessed with Ernest Hemingway. Despite the help of an ex-bootlegger gone legit, an old girlfriend turned lawyer, and a young singer looking for a break, things go from bad to worse when the only cop who believes he's innocent, is murdered. When Jim learns that Greeley is on his way to Key West, he suspects the doctor is going to kill Hemingway. With Boyle on his trail, Jim heads to the Keys to confront Greeley. He arrives in plenty of time to save Hemingway, but with a major hurricane on its way, he wonders if he'll have time to prove his innocence and save himself.