The Orexin/Hypocretin System: Functional Roles and Therapeutic Potential
Editat de Jim R. Fadel, Joshua A. Burken Limba Engleză Paperback – 11 ian 2019
- Provides an overview of new research on orexins/hypocretins
- Includes an overview of intracellular signaling and orexin physiology
- Discusses the effects on arousal, appetite, cognition, addiction and anxiety
- Examines orexin based therapies and their potential use in disorders
- Explores orexin receptors for drug development
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Specificații
ISBN-13: 9780128137512
ISBN-10: 0128137517
Pagini: 188
Dimensiuni: 152 x 229 x 16 mm
Editura: ELSEVIER SCIENCE
ISBN-10: 0128137517
Pagini: 188
Dimensiuni: 152 x 229 x 16 mm
Editura: ELSEVIER SCIENCE
Public țintă
Researchers, clinicians, postdoctoral fellows and graduate students in behavioral neuroscience, clinical neuroscience, neuroendocrinology, pharmacology, psychiatry, and psychologyCuprins
Part 1: Introduction
1. Hypocretins (orexins): 20 years of dissecting arousal circuits
2. Orexins and motivated behaviors
Part 2: Orexins and Sleep
3. Orexins and the stabilization of wake/sleep states
4. Orexins and narcolepsy in animal models
Part 3: Orexins and Feeding
5. Orexin’s role in motivated behavior for food
6. Orexin drives energy expenditure
Part 4. Orexins and Drug Abuse
7. Orexins/hypocretins and addiction
8. Hypocretin 1 receptor regulation of dopaminergic signaling and motivated behavior
9. Orexins and opioid addiction
Part 5: Orexins and Cognition
10. Orexins and cognition: neurochemical and anatomical substrates
11. The hypocretin/orexin system and fear learning
Part 6: Orexins and Psychological Disorders
12. Orexins and anxiety disorders
13. Orexins as targets for treating brain disorders
1. Hypocretins (orexins): 20 years of dissecting arousal circuits
2. Orexins and motivated behaviors
Part 2: Orexins and Sleep
3. Orexins and the stabilization of wake/sleep states
4. Orexins and narcolepsy in animal models
Part 3: Orexins and Feeding
5. Orexin’s role in motivated behavior for food
6. Orexin drives energy expenditure
Part 4. Orexins and Drug Abuse
7. Orexins/hypocretins and addiction
8. Hypocretin 1 receptor regulation of dopaminergic signaling and motivated behavior
9. Orexins and opioid addiction
Part 5: Orexins and Cognition
10. Orexins and cognition: neurochemical and anatomical substrates
11. The hypocretin/orexin system and fear learning
Part 6: Orexins and Psychological Disorders
12. Orexins and anxiety disorders
13. Orexins as targets for treating brain disorders