Struggling to comprehend his new and sometimes cruel reality involving poverty, disease, drug addiction, and racial tension, the young intern, Thomas Spezia, is not prepared for the rigors of training and the gritty reality of St. Louis City Hospital. When his mentor, Dr. Skelton, assigns the case of Lori Raines, a terminally ill patient, Thomas becomes overwhelmed by her needs and the demands of her philandering husband and so he embarks on a treacherous road to self-discovery that indelibly transforms his life. Everyone has a dream, but every dream has a price. Thomas must answer the question that gnaws at him, day and night: Has the price become too high?