After middling pharmaceutical company executive Clyde Young boards an airplane to attend a national meeting to make a presentation concerning his employer's premium drug, his schedule is thrown into a curve when terrorists hijack the plane. After refusing to keep his head down, he is hurled out with a parachute that barely functions. He is able to survive in the wilderness, but upon his arrival back to civilization, no one believes his story. They assume he is one of the terrorists that hijacked the airplane, so Young escapes to Las Vegas to determine why he was targeted and who was responsible for his ordeal. He lives as a street person and meets four people who believe his story: a sociopath, a prostitute, an alcoholic doctor and a pickpocket.
These people become his allies. They travel with him to the east coast and then to Europe. As Young continues his investigation, he discovers abuses on the part of his employer that could result in mortal danger for innumerable innocent patients. He must act quickly to expose the danger by staying one step ahead of the unknown criminals who are closing in on him and his allies.