Elio Barati's perfumery shop in Florence marks its entrance with a mosaic star. This shop immerses Elio in the artisanal world he loves, but he harbors a regret. As a young man he created a full-fledged perfume of jasmine, iris, and cypress at the renowned Ecole des Parfumeurs in Grasse-a fragrance his idealism and stubbornness boxed away before ever bringing it to light. A second star now brightens Elio's life, his daughter Romina, an artist. She has her father's unrealized talent, a precise and intuitive sense of smell. She's also inherited more challenging traits of Elio's: unbridled ambition and an insatiable wonder for the world. But changes ripple through modern-day Florence. Artisan traditions wane; and when Romina tells her father she has no intention of running the family business Elio fights to hold on to the Florence he cherishes. Confronting the lost opportunities of his youth, Elio is thrust into this journey by five spirited women: his Greek mother, Elena; his mentor Palma; his soul mate, Marina; his astronomer wife, Sofia; and finally his beautiful artist daughter, who like the city of her birth, shows him how tradition and modernity can and must co-exist. Now he must alter his own path by harnessing the transformative powers of the fine and artisanal arts.