In the late 26th century, overpopulation on Earth is reaching the breaking point, and humanity must find new frontiers. The terraforming of Mars has taken centuries but is now complete. The colonization of Mars by humanity is an epoch-making event, but an unintended side effect of the terraforming process unleashes a horror no one could ever have imagined…

Thailand, twenty years after the ill-fated Bugs 2 mission - Two American U-NASA agents arrive to find Akari Hizamaru, a child born after the operation, and recruit him for Annex 1, a new mission to Mars. The purpose of Annex 1 is to research the origins of a new disease that is ravaging the earth. But the reasons why U-NASA would need the incredible powers that Hizamaru possesses are still a closely guarded secret. Once again, humanity launches an expedition to Mars that has frightening implications for the future.